CAR T-cell therapy

CAR T-cell therapy

A type of treatment in which a patient’s T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient’s blood. Then the gene for a special receptor that binds to a certain protein on the patient’s cancer cells is added in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion. CAR T-cell therapy is being studied in the treatment of some types of cancer. Also called chimeric antigen receptor T-cell therapy.

The Science behind CAR-T Therapy

CAR-T therapy is part of a larger group of next-generation treatments known as ‘Adoptive Cell Transfer’. In these treatments, the patient’s own immune cells are collected and genetically engineered to target and kill cancer cells. The engineered immune
T cells are then proliferated and tested in the laboratory, usually taking days to weeks. The immune cells are then injected back into the patient and the termination of cancer cells begins.

The outstanding results of CAR-T Cell Treatment

CAR-T first appeared in what is now a well-known study focusing on ALL in children resistant to therapy or with recurrent cancer, back in 2015.
It is important to note that ALL is the most common cancer in children and a leading cause of death from childhood cancer. In this study, 90% of the patients treated with CAR-T stopped showing any signs of ALL (this is called CR or “Complete Remission”). In fact, many of them had no signs of recurrence even long after the treatment, which could be defined as healing. Later studies from several countries showed similar outstanding results.

CAR-T is already approved world-wide

As more results of the impressive effectiveness of CAR-T treatment continued to surface, the American Food and Drug Agency (FDA) approved the treatment for both severe ALL and severe Lymphoma.
In fact, 186 American studies and 153 international studies continue to expand our knowledge regarding the potential of CAR-T as a revolutionary treatment for ALL, Lymphomas and many other diseases.
It is important to note that CAR-T Therapies are currently also evaluated as first-line treatments across the world, including in the Israeli hospitals Zand Medicine works with.

The field of CAR-T Treatment

According to the International Lymphoma Foundation, “while the number of US government-funded researches has decreased, a race for new cancer therapies has led to a 500% growth in biotech investments in Israel”. These investments are promoting top Israeli hospitals to offer world-class CAR-T treatment at a fraction of the cost in American medical centers.

B Cell Lymphoma

CD19 CAR-T – 90% CR

B-Cell Acute Lymphoblastic Leukemia (B-ALL)

​CD19 CAR-T – 90% CR

Multiple Myeloma (MM)

BCMA CAR-T
82% Long-Term Survival

Acute Myeloid Leukemia (AML)

CD19 CAR-T
Newest Procedure
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Chimeric Antigen Receptor T cells therapy (CAR-T) is a cutting-edge treatment, approved by the FDA for a growing number of diseases, primarily hematologic cancers.
In this almost sci-fi treatment, special medical team engineers the immune system to fight a disease, showing outstanding results.
The introduction of CAR-T treatment to the medical world dramatically changed the course of disease for patients suffering from Acute B Lymphocytic Leukemia (B-ALL), B cell lymphoma, Multiple Myeloma and Acute Myeloid Leukemia (AML).

Zand Medicine helps you to receive affordable CAR-T treatments from the best medical teams worldwide without compromising on the quality.

While the average cost of CAR-T therapy in the US starts at 440,000 USD, our international options will cost only 90,000-110,000 USD.

As part of our CAR-T treatment package, we provide:

• Online medical consultancies about the efficacy of CAR-T treatment for you
• CAR-T Cell Treatment in a leading, experienced medical center.
• Travel and accommodation arrangements (upon request)
• All airport and hospital transfers
• Multi-lingual support and local escort teams, also providing translations for your medical documentation.

Zand Medicine – Your guardian angels abroad

We know that traveling abroad to receive medical treatment can be a stressful and challenging experience.
We promise we can make it much smoother.
Our executive case manager assigned to you will take your case through hospital’s bureaucracies, get all your questions answered and assist you in any way possible to assure that you stay is as comfortable as possible.
Our local team will meet you as you arrive at the local airport, accompany you through your treatment and wave you farewell as you depart back home.

We will bridge all the medical, cultural and lingual gaps for you.

How to apply for CAR-T therapy?

Zand Medicine works with the top hospitals that shine in the field of CAR-T treatment.

=> Fill in the contact form. Add a short description of your case history and of your current condition.
Our case manager will contact you shortly and guide you through.
Remember, the earlier you start your treatment, the higher your chances to achieve Complete Remission (CR).

What’s next?

1. Contact us: fill the contact form, send an email or give us a call.

2. Send us your medical documents. We will translate and forward them to our experts.

3. We will send you the various possible treatment plans and prices, and help you select the best option for you.

4. If you’d like, we can help in organizing your flights and accommodation.

5. Our personal attendant will meet you at the arrivals gate and accompany you throughout the course of your treatment.

6. We will send the translated release documents and keep in touch with you even after you leave.

Always here for you,

Zand Medicine